欧盟评估3-植酸酶FLF1000和FSF10000作为猪饲料添加剂的安全性

 

　　据了解，该添加剂含有的3-植酸酶是由转基因巴斯德毕赤酵母（Komagataella phaffii） 生产的。经过评估，专家小组得出结论，该添加剂在建议使用水平（1000 FTU/kg）下对育肥猪和小型生长猪种是安全的。部分原文报道如下：

 

　　Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on the safety of 3‐phytase FLF 1000/FSF 10000 as a feed additive for pigs for fattening and minor porcine species for growing. This additive contains 3‐phytase produced by a genetically modified strain of Komagataella phaffii and it is authorised in its liquid FLF 1000 and solid form FSF 10000 as a feed additive for chickens for fattening, laying hens, chickens reared for laying and for minor poultry species for fattening or reared for laying or for breeding. The FEEDAP Panel has adopted an opinion regarding the use of this product as a feed additive in pigs for fattening and minor porcine species for growing. In that opinion, the FEEDAP Panel concluded that the use of the product as a feed additive would raise no concerns for the consumer safety nor for the environment but that the additive should be regarded as a potential respiratory sensitizer. The Panel also concluded that the additive has a potential to be efficacious in improving the phosphorus utilisation in the target species. However, the Panel could not conclude on the safety for the target species due to the limitations identified in the data provided. The applicant has now complemented the information and made it available to the Panel. The tolerance trial was done in weaned piglets in which the animals received up to 10 times the recommended dose of 1,000 FTU /kg feed. The results showed no adverse effects of the phytase on the performance of the animals or on the haematological and biochemical parameters measured in blood. Therefore, the Panel concluded that the additive (3‐phytase FLF 1000 and FSF 10000) is safe for pigs for fattening and minor growing porcine species at the recommended dose of 1,000 FTU /kg feed.

 

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